Cecilia is an American nun of devout faith, embarking on a new journey in a remote convent in the picturesque Italian countryside. Cecilia's warm welcome quickly devolves into a nightmare as it becomes clear her new home harbors a sinister secret and unspeakable horrors.

Released from his chained coffin after nearly 200 years, Barnabas Collins arrives at the Collinwood estate claiming to be a relative from England. Although noticing Barnabas' resemblance to his 'ancestor' in the foyer portrait, the Collins family does not realize he is the same Barnabas who lived at Collinwood in the 18th century. As Barnabas moves into the Old House on the property, those around him are unaware of the horrors that will soon follow....

In 1970, Daphne pleads with the ghost of Gerard, begging him to spare the children at Collinwood from harm. Using the stairway through time, Julia escapes to the year 1840 and anxiously awaits Barnabas to join her, posing as his sister. Angelique returns and learns that Barnabas has been released from his coffin. She warns him that unless they live together as man and wife, she will cause his true love, Roxanne, to become a vampire. Contains 40 complete...

At the altar of the Leviathans, Barnabas is attacked by a bat and is again a victim of the vampire curse. Dr. Hoffman hopes to cure Barnabas by resuming her medical treatment of him through a series of injections. Leviathan leader Jeb Hawkes summons an army of zombies to kidnap Julia, hoping she can make him human. Barnabas is startled to discover a room in Collinwood's east wing which serves as a portal to a parallel universe. Contains 40 complete...

In 1897, Quentin and Magda discover the mysterious urn which contains the flames of life for Laura, an immortal Phoenix. Magda places a curse on Quentin, which causes him to turn into a werewolf during a full moon. Mentalist Pansy Faye uses her psychic abilities during a seance to help determine the fate of servant Dirk Wilkins, who rises as a vampire after being attacked by Barnabas. Contains 40 complete episodes.

In 1795, Barnabas has risen as a vampire. Using her supernatural powers, Angelique tricks Josette into going to Widows' Hill, where Josette sees a horrifying vision of her future should she become Barnabas' bride. Reverend Trask persuades Nathan to testify against Victoria, who is on trial for witchcraft. Barnabas vows revenge against Trask. Contains 40 complete episodes.

Hoping to free himself and the entire Collins family of Angelique's evil schemes, Barnabas hires artist Sam Evans to age her portrait, causing Angelique to rapidly age into a 200-year-old woman. The ghost of Reverend Trask appears at the Old House to seek vengeance against Barnabas for the tragedies in Collinsport of 1795. Professor Stokes questions Victoria about her trip back in time and what she knows about Angelique. Contains 40 complete episodes....

Barnabas decides that Maggie must serve as the life force in the bizarre experiment he and Dr. Hoffman plan to conduct in the hope of creating a mate for Adam. Maggie begins to remember how Barnabas kidnapped her months before and attempted to make her his bride. As a vampire, Angelique attacks Barnabas and places him under her supernatural control. Eve informs Jeff they have both lived before as lovers in the 1790s. Contains 40 complete episodes....

In 1795, after being convicted of witchcraft, Victoria waits to be hanged at the gallows. In 1968, Victoria reappears during a seance at Collinwood and Barnabas fears that she has learned his secret from her time in the past. Roger surprises the family by introducing his new wife Cassandra, whom Barnabas realizes is actually Angelique, the witch who cursed him as a vampire in 1795. Contains 40 complete episodes.

In the year 1995, Barnabas and Dr. Hoffman wonder what has happened to the Collins family when they find the Collinwood estate abandoned and in ruins. They learn that both Carolyn and Quentin have gone insane. In 1970, Barnabas is stunned when he meets astrologist Sebastian Shaw's assistant, Roxanne, who is identical to the Roxanne that Barnabas knew in parallel time. Contains 40 complete episodes.